Rejuran Healer vs Rejuran S—Which Is Right for Your Skin in SG?

Introduction

In Singapore’s modern aesthetic landscape, Rejuran has become a household name — and for good reason. Known as the “skin healer injection,” this Korean innovation has transformed how people approach anti-aging and skin repair. Instead of merely filling wrinkles or freezing muscles, Rejuran works at the cellular level, healing and rejuvenating the skin from within.

But as the treatment’s popularity grows, many Singaporeans find themselves asking: “Should I get Rejuran Healer or Rejuran S?”

Both are part of the same Rejuran family and share the same foundation — polynucleotide (PN) derived from salmon DNA — but they serve different purposes. While Rejuran Healer focuses on overall skin rejuvenation and elasticity, Rejuran S targets deeper concerns like acne scars and textural irregularities.

In this complete 2025 guide, we’ll help you understand the key differences, benefits, costs, and ideal treatment schedules for both versions, and how to decide which one suits your skin goals.

Whether you’re seeking smoother, glowing skin or looking to improve stubborn scars, this comparison will give you the clarity you need — with expert insights from Dr Plus Clinic Singapore, a trusted name in safe and effective Rejuran treatments.


What Is Rejuran?

The Science Behind the Skin Healer

Rejuran is a non-surgical injectable treatment designed to repair, regenerate, and rejuvenate the skin. Its main active ingredient — polynucleotides (PN) — are long DNA fragments extracted and purified from salmon. These DNA molecules are biocompatible with human tissue, meaning they work harmoniously with your skin cells to promote healing.

When injected into the dermis, Rejuran stimulates:

Over time, these effects lead to visibly smoother, firmer, and more radiant skin — all without altering your natural features.


Why Rejuran Became So Popular in Singapore

Singapore’s tropical weather and lifestyle accelerate photoaging and skin damage. Constant exposure to UV rays, air-conditioning, and humidity weakens the skin barrier, leading to fine lines, pigmentation, and enlarged pores.

Rejuran addresses these issues by working from within, instead of on the surface like creams or serums. It’s a biological repair solution that rebuilds the foundation of healthy skin — making it especially effective for Singaporeans seeking natural anti-aging and scar improvement results.


The Different Types of Rejuran

While Rejuran Healer and Rejuran S are the most popular, the full Rejuran range includes several specialised formulations:

TypePurposeTarget Area
Rejuran HealerGeneral skin rejuvenationFace, neck, décolletage
Rejuran SScar repair and texture improvementAcne scars, surgical scars
Rejuran I (Eye)Delicate under-eye rejuvenationUnder-eye area
Rejuran HB (Hydro Booster)Deep hydration + repairFace, neck

For this article, we’ll focus on the two most in-demand options in SingaporeRejuran Healer and Rejuran S — and explore which one fits your needs best.


What Is Rejuran Healer?

Overview

Rejuran Healer is the flagship formulation and the one that started it all. Its main goal is to restore skin health, elasticity, and radiance.

The treatment involves microinjections of PN molecules evenly across the face. These molecules penetrate the dermis and trigger natural cell regeneration, repairing micro-damage accumulated from aging, sun exposure, and pollution.

Ideal For

Benefits of Rejuran Healer

  1. Smooths Fine Lines & Wrinkles
    By stimulating fibroblast activity, it rebuilds collagen networks and softens fine lines.
  2. Improves Elasticity & Firmness
    Skin feels bouncier and tighter as collagen density increases.
  3. Refines Pores & Texture
    Healed dermal layers create a smoother, more refined skin surface.
  4. Brightens & Hydrates
    Improves overall radiance by increasing cellular turnover and moisture retention.
  5. Repairs the Skin Barrier
    Strengthens weak or damaged skin prone to redness or sensitivity.

Areas Commonly Treated


What Is Rejuran S?

Overview

Rejuran S was designed as a specialised version of Rejuran Healer for acne scars and skin indentations. It has a higher viscosity and concentration of polynucleotides, making it more effective for structural repair.

Instead of being injected across the entire face, Rejuran S is targeted to specific depressed or pitted areas, stimulating collagen formation and dermal remodelling.

Ideal For

Benefits of Rejuran S

  1. Fills Depressed Acne Scars Naturally
    Collagen regeneration gradually lifts and evens out scarred areas.
  2. Improves Skin Density
    Rebuilds damaged dermal tissue for thicker, stronger skin.
  3. Smooths Surface Texture
    Reduces roughness caused by scar tissue or chronic inflammation.
  4. Long-Term Regeneration
    Works progressively for lasting structural improvement without adding artificial volume.

Areas Commonly Treated


Key Differences Between Rejuran Healer and Rejuran S

FeatureRejuran HealerRejuran S
Main FunctionOverall skin rejuvenationScar repair & collagen remodelling
ViscositySofter and smootherThicker and denser
Injection TechniqueMicroinjections across faceTargeted deep injections
Treatment FocusTexture, tone, elasticityAcne scars, pits, deep irregularities
Recovery Time1–2 days of mild bumps2–3 days, slightly longer swelling
FrequencyMonthly for 3–4 sessionsMonthly for 3–6 sessions
Results Timeline3–6 weeks for glow & texture6–12 weeks for scar repair
Best ForEarly aging, dullness, dehydrationAcne scars, damaged skin

How Rejuran Works on the Skin

Step 1: Injection and Cellular Activation

The doctor administers small injections of Rejuran into the mid to deep dermis.

Step 2: Polynucleotide Integration

The PN molecules are absorbed by fibroblast cells, which begin producing collagen, elastin, and extracellular matrix.

Step 3: Skin Repair & Renewal

Over the following weeks, these processes strengthen and repair the skin’s structure, resulting in smoother texture and improved tone.

Step 4: Long-Term Rejuvenation

With consistent treatments, the skin achieves lasting repair — not just surface improvement but biological regeneration.


Treatment Schedule

Rejuran Healer

PhaseFrequencyPurpose
Initial3–4 sessions, 3–4 weeks apartActivate regeneration
Maintenance1 session every 6 monthsSustain collagen renewal

Rejuran S

PhaseFrequencyPurpose
Initial3–6 sessions, 3–4 weeks apartStimulate collagen in scars
MaintenanceEvery 6–9 monthsPreserve results

Each session takes about 30–45 minutes including numbing and post-care.


What to Expect During a Session

1. Consultation

Your doctor analyses your skin condition and identifies target areas.

2. Numbing Cream Application

Applied for 20–30 minutes to ensure comfort.

3. Injection Process

Fine needles or injector devices deliver microdroplets of Rejuran precisely.

4. Post-Treatment Cooling

A soothing mask or cooling device reduces redness and swelling.

5. Recovery

Tiny bumps fade within 24–48 hours for Rejuran Healer and slightly longer for Rejuran S.


Recovery and Aftercare

Do’s

Don’ts


Visible Results

TimelineRejuran HealerRejuran S
1 WeekImproved hydration and softnessSlight texture improvement
4 WeeksGlow and smoother toneNoticeable scar reduction
8 WeeksFirmer, radiant skinContinued collagen filling of scars
3–6 MonthsPeak rejuvenation resultsSignificant scar fading and smoother skin

Both treatments deliver natural, progressive improvements — not overnight transformations.


Cost of Rejuran Healer vs Rejuran S in Singapore (2025)

Treatment TypeAverage Price per Session (SGD)Treatment Area
Rejuran Healer$450 – $700Full face / neck
Rejuran S$450 – $800Scar areas (cheeks, temples, chin)
Combined Treatment$800 – $1,200For both rejuvenation + scars

Package Prices

Prices depend on treatment area, skin condition, and doctor’s expertise.


Can You Combine Rejuran Healer and Rejuran S?

Yes. In fact, combining both treatments can be an excellent strategy for patients who want full-face rejuvenation with targeted scar repair.

Combination Plan Example:

  1. Session 1–3: Full-face Rejuran Healer
  2. Session 4–6: Targeted Rejuran S for acne scars

This sequence helps build a stronger skin foundation before tackling deeper scars, maximising overall results.


Comparing Results: Rejuran Healer vs Rejuran S

GoalRejuran HealerRejuran S
Smoother, youthful glow★★★★★★★☆☆☆
Scar reduction★★★☆☆★★★★★
Fine line improvement★★★★★★★★★☆
Hydration & radiance★★★★★★★★☆☆
Skin firmness★★★★☆★★★★☆
DowntimeMinimal (1–2 days)Slightly longer (2–3 days)

Why Choose Rejuran Treatments at Dr Plus Clinic Singapore

When it comes to advanced injectables like Rejuran, precision, product authenticity, and doctor expertise matter most.

At Dr Plus Clinic Singapore, every Rejuran treatment is conducted under strict medical protocols by experienced aesthetic doctors.

1. Doctor-Led Expertise

All Rejuran injections are performed or supervised by qualified doctors trained in facial anatomy and skin regeneration techniques.

2. Authentic, HSA-Approved Products

The clinic uses only authentic Rejuran formulations, ensuring treatment safety and effectiveness.

3. Customised Plans for Each Patient

Every treatment is tailored to individual skin needs — whether for rejuvenation, scars, or both.

4. Minimal Downtime Protocols

Special post-laser cooling and healing care help reduce downtime and accelerate recovery.

5. Transparent Pricing

No hidden costs, no aggressive upselling — just clear, professional advice and care.

6. Natural, Long-Lasting Results

Dr Plus Clinic focuses on achieving a subtle, radiant enhancement that looks refreshed — never overdone.

If you’re looking for results that are natural, medically safe, and long-lasting, Dr Plus Clinic Singapore offers expert Rejuran care you can trust.


Frequently Asked Questions (FAQ)

1. Can I do Rejuran Healer and S together?

Yes. Many patients start with Rejuran Healer to strengthen the skin before targeting deeper scars with Rejuran S.

2. How long do results last?

Typically 6–12 months, with maintenance recommended twice a year.

3. Is Rejuran painful?

Mild discomfort is normal, but numbing cream and cooling masks make the treatment comfortable.

4. Can Rejuran be done on acne-prone skin?

Yes. It helps heal inflammation and strengthens the barrier, reducing future breakouts.

5. Are there side effects?

Mild redness or bumps fade within a day or two. Bruising is rare and temporary.

6. When can I wear makeup?

After 24 hours, once the skin surface is calm.

7. Is Rejuran suitable for men?

Absolutely. Men benefit from improved texture, smaller pores, and stronger skin structure.


Conclusion

Both Rejuran Healer and Rejuran S belong to the same powerful family of bio-regenerative injectables — but they serve distinct purposes:

The best choice depends on your specific goals. For general rejuvenation, Rejuran Healer is ideal. For acne scars or deep texture repair, Rejuran S offers targeted healing. And for those seeking both — combining them provides the most comprehensive transformation.

At Dr Plus Clinic Singapore, every Rejuran treatment is personalised, doctor-led, and rooted in medical precision. Using advanced techniques and genuine products, the clinic ensures your results are natural, radiant, and truly restorative.

If you’re ready to repair and renew your skin from within, book your consultation today with Dr Plus Clinic Singapore — where science, safety, and beauty meet perfectly for healthy, glowing skin that lasts.